Welcome to the resource topic for 2015/133
Title:
Private Computation on Encrypted Genomic Data
Authors: Kristin Lauter, Adriana Lopez-Alt, Michael Naehrig
Abstract:A number of databases around the world currently host a wealth of genomic data that is invaluable to researchers conducting a variety of genomic studies. However, patients who volunteer their genomic data run the risk of privacy invasion. In this work, we give a cryptographic solution to this problem: to maintain patient privacy, we propose encrypting all genomic data in the database. To allow meaningful computation on the encrypted data, we propose using a homomorphic encryption scheme. Specifically, we take basic genomic algorithms which are commonly used in genetic association studies and show how they can be made to work on encrypted genotype and phenotype data. In particular, we consider the Pearson Goodness-of-Fit test, the D’ and r^2-measures of linkage disequilibrium, the Estimation Maximization (EM) algorithm for haplotyping, and the Cochran-Armitage Test for Trend. We also provide performance numbers for running these algorithms on encrypted data.
ePrint: https://eprint.iacr.org/2015/133
See all topics related to this paper.
Feel free to post resources that are related to this paper below.
Example resources include: implementations, explanation materials, talks, slides, links to previous discussions on other websites.
For more information, see the rules for Resource Topics .